Search Result

Search Results for " bb 1 "

Targets

Compounds

Natural Products

1748

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T13932	TLR1		Others , MyD88
	TLR1 is a cell-penetrating Toll/IL-1 receptor/resistance (TIR) domain/BB-Loop mimic and inhibits IL-1 receptor-mediated responses.		Others , MyD88
T6011	Batimastat	BB94	MMP
	Batimastat (BB94) (BB-94) is an effective, broad-spectrum matrix metalloprotease (MMP) inhibitor. Batimastat induces extracellular matrix degradation and inhibits angiogenesis, tumor growth and invasion, and metastasis.		MMP
T6885	Marimastat	BB2516,KB-R8898,TA2516	MMP
	Marimastat (BB2516) (BB-2516) is a potent, broad spectrum matrix metalloprotease (MMP) inhibitor. MMP-9 (IC50=3 nM), MMP-1 (IC50=5 nM), MMP-2 (IC50=6 nM), MMP-14 (IC50=9 nM)and MMP-7 (IC50=13 nM).		MMP
T60775	BB 0305179
	BB 0305179 (compound 59) inhibits the toxicity of a specific PrP mutant carrying a deletion in the hydrophobic domain. BB 0305179 is a potent anti-prion agent (IC 50 = 4.7 μM) [1].
T10482L	BB-Cl-Amidine hydrochloride	BB-Cl-Amidine hydrochloride (1802637-39-3 free base)	Others
	BB-Cl-Amidine hydrochloride is an inhibitor of peptidylarginine deminase (PAD) [1].		Others
T82171	HS-291		ROS Kinase
	HS-291 is a HtpG inhibitor targeting Borrelia burgdorferi (Bb), composed of BX-2819 (high affinity for Bb HtpG), a PEG linker, and Verteporfin (a photoactive toxin). Upon light activation, HS-291 generates reactive oxyge...		ROS Kinase
T10461	Batimastat sodium salt	BB-94 sodium salt	MMP
	Batimastat (BB-94) sodium salt is a broad-spectrum MMP inhibitor (IC50s: 3, 4, 4, 6, and 20 nM for MMP-1, MMP-2, MMP-9, MMP-7, and MMP-3).		MMP
T36632	BB-Cl-Yne
	BB-Cl-Yne is a cell-permeable derivative of the protein arginine deiminase (PAD) inhibitor BB-Cl-amidine that contains an alkyne moiety for use in click chemistry reactions. BB-CL-Yne inhibits PAD1-4 with Kinact/KI value...
T67442	CGP-53716
	The growth factors, platelet-derived growth factor (PDGF) and basic fibroblast growth factor (bFGF) play major roles in enhanced smooth muscle cells growth in rodent blood vessels after vascular injury. Tyrosine kinase i...
T75945	BA 1 TFA
	BA 1 TFA acts as a potent agonist for the bombesin (BB) family of receptors, exhibiting high affinity binding to Bombesin receptor subtype-3 (BRS3), gastrin-releasing peptide receptor (GRPR), and neuromedin B receptor (N...
T79730	LB244		STING
	LB244, a homologue of BB-Cl-amidine, functions as an orally effective STING inhibitor with an EC50 value of 0.8 μM, applicable in the treatment of STING-dependent inflammatory diseases. However, pharmacokinetic studies h...		STING
T35817	Photoswitchable PAD Inhibitor (technical grade)
	Photoswitchable PAD inhibitor is a photoactivated protein arginine deiminase (PAD) inhibitor and a derivative of BB-Cl-amidine that contains an azobenzene photoswitch allowing optical control of PAD activity.1 Without ph...
T36547	Quazinone
	Quazinone is a selective inhibitor of phosphodiesterase 3 (PDE3) with positive inotropic and vasodilating properties.1,2 It induces relaxation of precontracted isolated human cavernous smooth muscle (IC50 = 4.2 μM).1 Qua...

Compounds

TLR1

T13932

Synonym:

Target: Others, MyD88

Synonym: BB2516,KB-R8898,TA2516

BB-Cl-Amidine hydrochloride

T10482L

Synonym: BB-Cl-Amidine hydrochloride (1802637-39-3 free base)

Batimastat sodium salt

T10461

Synonym: BB-94 sodium salt

Photoswitchable PAD Inhibitor (technical grade)

Cat No.	Product Name	Synonyms	Targets
T3323	Ursonic Acid	CCRIS 7123,NSC4060,Prunol,3-Ketoursolic acid,Malol,TOS-BB-0966	Apoptosis , HIV Protease , Endogenous Metabolite
	Ursonic Acid (TOS-BB-0966) belongs to the family of Ursane Triterpenes whose structure is based on the pentacyclic ursane skeleton. It has potential as HIV-1 Protease Inhibitor.		Apoptosis , HIV Protease , Endogenous Metabolite
T6S0655	Corynoxeine		ERK
	1. Corynoxeine is a potent ERK1/2 inhibitor of key PDGF-BB-induced VSMC proliferation and may be useful in the prevention and treatment of vascular diseases and restenosis after angioplasty.		ERK
T3S0335	Soyasaponin Bb	Soyasaponin I	NF-κB , Caspase
	1. Soyasaponin Bb (Soyasaponin I) can suppress Eca-976 cell growth, reverse effects on over expression of c-met, VEGF, and induce cell apoptosis through inhibiting HDAC1-NF-kappaB and activating PETEN and caspase-3 signa...		NF-κB , Caspase
TN2354	Methylnissolin	3-Hydroxy-9,10-dimethoxyptercarpan	ERK , PDGFR
	Methylnissolin (3-Hydroxy-9,10-dimethoxyptercarpan) is derived from Astragalus and has antibacterial and anti-cancer effects.		ERK , PDGFR
TN2063	Physalin B	NSC-287088	Apoptosis , NF-κB , Akt , PI3K , Nrf2 , NOD
	Physalin B is one of the major active compounds from the Solanaceae family of plants and has a wide range of biological activities for the treatment of inflammatory eczema and herpes, among other diseases.Physalin B amel...		Apoptosis , NF-κB , Akt , PI3K , Nrf2 , NOD
T73681	Aspidin BB
	Aspidin BB, a phloroglucinol derivative isolated from the aerial part of Dryopteris championii, exhibits anticancer activity. It induces cell cycle arrest and apoptosis in human ovarian HO-8910 cells [1] [2].

Natural Products

Ursonic Acid

T3323

Synonym: CCRIS 7123,NSC4060,Prunol,3-Ketoursolic acid,Malol,TOS-BB-0966

Target: Apoptosis, HIV Protease, Endogenous Metabolite

Synonym: Soyasaponin I

Target: NF-κB, Caspase

Methylnissolin

TN2354

Synonym: 3-Hydroxy-9,10-dimethoxyptercarpan

Target: Apoptosis, NF-κB, Akt, PI3K, Nrf2, NOD

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-01142	ICAM-1/CD54 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	ICAM-1/CD54 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51 kDa and the accession number is A0A384MEK5.
TMPY-00981	ICAM-1/CD54 Protein, Human, Recombinant (aa 1-480,DDDDK)	Human	HEK293 Cells
	ICAM-1/CD54 Protein, Human, Recombinant (aa 1-480,DDDDK) is expressed in HEK293 mammalian cells. The predicted molecular weight is 50.2 kDa and the accession number is A0A384MEK5.
TMPY-00674	B7-1 Protein, Human, Recombinant	Human	HEK293 Cells
	B7-1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.5 kDa and the accession number is A0N0P2.
TMPK-00497	ICAM-1/CD54 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Intercellular adhesion molecule-1 (ICAM-1; CD54) is a 90 kDa member of the immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-...
TMPK-00872	ICAM-1/CD54 Protein, Canine, Recombinant (His)	Canine	HEK293 Cells
	Intercellular adhesion molecule-1 (ICAM-1; CD54) is a 90 kDa member of the immunoglobulin (Ig) superfamily and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-...
TMPY-03128	LAIR1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	LAIR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.6 kDa and the accession number is Q8BG84-6.
TMPY-06777	ICAM-1/CD54 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	ICAM-1/CD54 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 52.77 kDa and the accession number is NP_000192.2.
TMPY-02598	LAIR1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	LAIR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14 kDa and the accession number is Q8BG84-1.
TMPY-06778	ICAM-1/CD54 Protein, Human, Recombinant (aa 1-480, LEVLFQ)	Human	HEK293 Cells
	ICAM-1/CD54 Protein, Human, Recombinant (aa 1-480, LEVLFQ) is expressed in HEK293 mammalian cells. The predicted molecular weight is 50.31 kDa and the accession number is NP_000192.2.
TMPY-00825	ICAM-1/CD54 Protein, Human, Recombinant (His & hFc)	Human	HEK293 Cells
	ICAM-1/CD54 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 77.4 kDa and the accession number is A0A384MEK5.
TMPY-02750	Neuroligin-1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Neuroligin-1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 73.5 kDa and the accession number is Q99K10-1.
TMPY-05393	ICAM-1/CD54 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	ICAM-1/CD54 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 76.2 kDa and the accession number is A0A384MEK5.
TMPY-05379	B7-1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	B7-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.6 kDa and the accession number is A0N0P2.
TMPY-06298	B7-1 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	B7-1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 27.12 kDa and the accession number is A0N0P2.
TMPY-01063	B7-1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	B7-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.4 kDa and the accession number is A0N0P2.
TMPK-00178	B7-1 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligan...
TMPK-00179	B7-1 Protein, Human, Recombinant (aa 35-242, His & Avi), Biotinylated	Human	HEK293 Cells
	Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligan...
TMPY-00205	CEACAM1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	CEACAM1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 70.3 kDa and the accession number is Q925P3.
TMPY-01676	CEACAM1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	CEACAM1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45 kDa and the accession number is Q925P3.
TMPY-04451	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&...
TMPY-02501	CD3D & CD3E Heterodimer Protein, Human, Recombinant	Human	HEK293 Cells
	CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1.
TMPY-03878	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)	Human	HEK293 Cells
	Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1.
TMPY-03745	CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)	Human	HEK293 Cells
	CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 31.05 kDa and the accession number is P04234-1&P07766-1.
TMPY-01968	CD32A Protein, Human, Recombinant (167 His, His)	Human	HEK293 Cells
	CD32A Protein, Human, Recombinant (167 His, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22 kDa and the accession number is P12318-1.
TMPY-04824	CTLA-4 Protein, Human, Recombinant	Human	HEK293 Cells
	CTLA-4 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 13.5 kDa and the accession number is P16410-1.
TMPY-04632	IL-15 Protein, Human, Recombinant	Human	E. coli
	IL-15 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 12.8 kDa and the accession number is P40933-1.
TMPY-00414	LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession number is A6NI73-1.
TMPY-04529	EGFR Protein, Human, Recombinant (aa 668-1210, His & GST)	Human	Baculovirus Insect Cells
	EGFR Protein, Human, Recombinant (aa 668-1210, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 89.1 kDa and the accession number is P00533-1.
TMPY-05201	Siglec-2/CD22 Protein, Human, Recombinant	Human	HEK293 Cells
	Siglec-2/CD22 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 75.2 kDa and the accession number is P20273-1.
TMPY-03782	Albumin Protein, Human, Recombinant	Human	P. pastoris (Yeast)
	Albumin Protein, Human, Recombinant is expressed in yeast. The predicted molecular weight is 66.4 kDa and the accession number is P02768-1.
TMPY-03956	Fas Ligand Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells su...
TMPY-01578	CD166/ALCAM Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CD166/ALCAM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.4 kDa and the accession number is Q13740-1.
TMPY-05277	IL-4R Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	IL-4R Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.5 kDa and the accession number is P24394-1.
TMPY-01920	BAFF/TNFSF13B Protein, Human, Recombinant (HEK293)	Human	HEK293 Cells
	BAFF/TNFSF13B Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 17 kDa and the accession number is Q9Y275-1.
TMPY-05220	TSLP Protein, Human, Recombinant (R127A & R130S, His)	Human	HEK293 Cells
	TSLP Protein, Human, Recombinant (R127A & R130S, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.2 kDa and the accession number is Q969D9-1.
TMPY-01076	Gp130/IL6ST Protein, Human, Recombinant (His & hFc)	Human	HEK293 Cells
	gp130/IL6ST Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 96 kDa and the accession number is P40189-1.
TMPY-00756	FGF-1 Protein, Human, Recombinant	Human	E. coli
	FGF-1 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16 kDa and the accession number is P05230-1.
TMPY-06418	R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.01 kDa and the accession number is Q6UXX9-1.
TMPY-05566	Siglec-2/CD22 Protein, Human, Recombinant (His, Solution)	Human	HEK293 Cells
	Siglec-2/CD22 Protein, Human, Recombinant (His, Solution) is expressed in HEK293 mammalian cells with His tag. The accession number is P20273-1.
TMPY-00322	DEC-205 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	LY75 (Lymphocyte Antigen 75) is a Protein Coding gene. It is broadly expressed in the lymph node, appendix, and other tissues. LY75 knockdown in SKOV3 cells resulted in predominant upregulation of functional pathways imp...
TMPY-02512	Alpha-Synuclein Protein, Human, Recombinant	Human	E. coli
	Alpha-Synuclein Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 14.5 kDa and the accession number is P37840-1.
TMPY-05030	PCDH7 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	PCDH7, a member of protocadherins family, functions as tumor suppressor in several human cancers. The human PCDH7 gene is localized in chromosome 4p15, which is often inactivated in human cancers, including bladder cance...
TMPY-06076	LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.7 kDa and the accession number is Q8N149-1.
TMPY-06873	FLT3 Ligand Protein, Human, Recombinant	Human	E. coli
	FLT3 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.75 kDa and the accession number is P49771-1.
TMPY-00742	EGFR Protein, Human, Recombinant (His)	Human	HEK293 Cells
	EGFR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.8 kDa and the accession number is P00533-1.
TMPY-04939	LAG-3 Protein, Human, Recombinant	Human	HEK293 Cells
	LAG-3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.3 kDa and the accession number is P18627-1.
TMPY-01209	IL-7R alpha/CD127 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IL-7R alpha/CD127 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is P16871-1.
TMPY-01964	CD16a Protein, Human, Recombinant (F176V, His)	Human	HEK293 Cells
	The Fc receptor with low affinity for IgG (FCGR3, or CD16) is encoded by 2 nearly identical genes, FCGR3A and FCGR3B, resulting in tissue-specific expression of alternative membrane-anchored isoforms. FCGR3A, it is also ...
TMPY-00694	Carbonic Anhydrase 12 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Carbonic Anhydrase 12 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.6 kDa and the accession number is O43570-1.
TMPY-03967	BTN3A3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	BTN3A3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is O00478-1.
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